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Cystic Fibrosis Clinical Isolates of Aspergillus fumigatus Induce Similar Muco-inflammatory Responses in Primary Airway Epithelial Cells

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On International Day for People with Disability this Sunday, The Kids Research Institute Australia celebrates the children and families we work with in our research, as we strive for better outcomes for kids with disability.

Ivacaftor and Airway Inflammation in Preschool Children with Cystic Fibrosis Authors: Paul McNally, Daryl Butler, Yuliya Karpievitch , Barry Linnane,

Effect of human rhinovirus infection on airway epithelium tight junction protein disassembly and transepithelial permeability. Rationale: No studies

The clinical significance of oropharyngeal cultures in young children with cystic fibrosis ABSTRACT In children with cystic fibrosis (CF) the

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Congratulations to prominent consumer advocate Catherine Hughes and The Kids Research Institute Australia honorary researcher Dr Noula Gibson, who have been named finalists in Research Australia’s 2023 Health and Medical Research Awards.

Parental Experience of Information and Education Processes Following Diagnosis of Their Infant With Cystic Fibrosis Via Newborn Screening. Abstract

Conditionally reprogrammed primary airway epithelial cells maintain morphology, lineage and disease specific functional characteristics The study of

Airway surface liquid pH is not acidic in children with cystic fibrosis Modulation of airway surface liquid (ASL) pH has been proposed as a therapy

We tested the hypothesis that treatment of CF epithelial cells with ivacaftor (Iva) or ivacaftor/lumacaftor (Iva/Lum) would improve control of rhinovirus infection.

Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis. Abstract Although destructive airway

Assessment of early lung disease in young children with CF: A comparison between pressure-controlled and free-breathing chest computed tomography