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A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiologyDiscover and replicate a locus indexed by rs77728904 at 9p21.3 associated with BCP-ALL susceptibility
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Home pesticide exposures and risk of childhood leukemia: Findings from the childhood leukemia international consortiumIn this investigation, the authors found an association between home pesticide exposure before birth and during a child's early years and acute lymphoblastic...
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Linked data research: a valuable tool in the ART fieldThis letter to the editor endorses data linkage studies and cites their potential value over other types of epidemiological studies within the field of...
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Home paint exposures and risk of childhood acute lymphoblastic leukemia: findings from the Childhood Leukemia International ConsortiumThis paper demonstrated that home paint exposure shortly before conception, during pregnancy, and/or after birth appeared to increase the risk of childhood ALL.
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Risk of cancer among children with birth defects: A novel approachThis novel approach aimed to prevent inflated hazard ratios arising from reverse causation, and allow identification of associations beyond those already...
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Folate pathway gene polymorphisms and risk of childhood brain tumors: Results from an Australian case-control studyRecent research suggests that maternal folic acid supplementation is associated with a reduced risk of childhood brain tumors (CBT); polymorphisms in folate...
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Birthweight and childhood cancer: Preliminary findings from the international childhood cancer cohort consortium (I4C)Background Evidence relating childhood cancer to high birthweight is derived primarily from registry and case-control studies.
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Breastfeeding and nutrition to 2 years of age and risk of childhood acute lymphoblastic leukemia and brain tumorsAcute lymphoblastic leukemia and childhood brain tumors are 2 of the most common forms of childhood cancer, but little is known of their etiology.
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Maternal supplementation with folic acid and other vitamins and risk of leukemia in offspring: a childhood leukemia international consortium studyOur results suggest that maternal prenatal use of vitamins and folic acid reduces the risk of both ALL and AML
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Confirmation of childhood acute lymphoblastic leukemia Variants, ARID5B and IKZF1, and interaction with parental environmental exposuresThe polygenic nature of childhood ALL predisposition together with the timing of environmental triggers may hold vital clues for disease etiology.