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Research

Predicting long term lung health outcomes in young adults born very preterm (WALHIP 19 year old follow-up)

Graham Shannon Elizabeth Hall Simpson Smith BAppSci PhD CRFS FANZSRS FThorSoc FERS BMedSci (hons), PhD PhD, MSc, BSc Honorary Research Associate Head

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Preterm Paediatric Inhaled Corticosteroids Intervention (PICSI)

Understanding if ongoing inflammation in the lungs contributes to the poor lung health experienced by some children who were born preterm.

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Lung function in African infants: A pilot study

Infant lung function (ILF) testing may provide useful information about lung growth and susceptibility to respiratory disease.

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Respiratory impedance and bronchodilator responsiveness in healthy children aged 2-13 years

There is limited information on changes in FOT outcomes in healthy children beyond the preschool years and the level of bronchodilator responsiveness (BDR)...

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Clinical investigation of respiratory system admittance in preschool children

We compared the ability of Ars, to standard oscillatory outcomes, to determine respiratory disease and differentiate responses to inhaled bronchial challenges.

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Air Trapping on Chest CT Is Associated with Worse Ventilation Distribution in Infants with Cystic Fibrosis

In school-aged children with cystic fibrosis (CF) structural lung damage assessed using chest CT is associated with abnormal ventilation distribution.

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Commentaries on Viewpoint: Standards for quantitative assessment of lung structure.

Commentaries on Viewpoint: Standards for quantitative assessment of lung structure. Instillation fixation and overinflation of the mouse lun

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Delayed airway epithelial repair is correlated with airway obstruction in young adults born very preterm

Nasal epithelial cells from young adults with a history of very preterm birth show delayed closure following scratch-wounding. Repair correlated with lung function, suggesting epithelial barrier integrity may play a role in preterm-associated lung disease.

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No association between in utero exposure to emissions from a coalmine fire and post-natal lung function

Studies linking early life exposure to air pollution and subsequent impaired lung health have focused on chronic, low-level exposures in urban settings. We aimed to determine whether in utero exposure to an acute, high-intensity air pollution episode impaired lung function 7-years later.

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Living with lung disease: experimental models to assess the long-term effects of prematurity

Laboratory models provide an important tool in helping to understand the cellular and molecular drivers of respiratory disease. Many animal models exist that model the neonatal outcomes of preterm birth.