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Showing results for "early life"

Down to Earth: Planetary Health and Biophilosophy in the Symbiocene Epoch

Advances in science have illuminated the role of the “ecological theatre”—the total living environment—in human health

Influence of maternal obesity on the long-term health of offspring

Including immediate implications for pregnancy complications, increasing evidence implicates maternal obesity having a major impact on long term child health.

Prenatal omega-3 fatty acid supplementation does not affect offspring telomere length and F2-isoprostanes at 12 years: A double blind, randomized controlled trial

Maternal n-3 LCPUFA supplementation did not provide sustained effects on postnatal oxidative stress and telomere length as observed in the offspring

Major grant supports innovative infant lung health study

A ground-breaking global clinical trial to improve the lifelong lung health of children born extremely prematurely has been awarded a Medical Research Future Fund (MRFF) International Clinical Trials Collaborations Grant totalling almost $3 million.

UV exposure and protection against allergic airways disease

Asthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity.

Metabolic dysfunction induced by a high-fat diet modulates hematopoietic stem and myeloid progenitor cells in brown adipose tissue of mice

Brown adipose tissue (BAT) may be an important metabolic regulator of whole-body glucose. While important roles have been ascribed to macrophages in regulating metabolic functions in BAT, little is known of the roles of other immune cells subsets, particularly dendritic cells (DCs). Eating a high-fat diet may compromise the development of hematopoietic stem and progenitor cells (HSPCs)-which give rise to DCs-in bone marrow, with less known of its effects in BAT. We have previously demonstrated that ongoing exposure to low-dose ultraviolet radiation (UVR) significantly reduced the 'whitening' effect of eating a high-fat diet upon interscapular (i) BAT of mice.

Expanding the clinical picture of the MECP2 Duplication syndrome

Perinatal characteristics, early childhood development and medical co-morbidities in MECP2 Duplication syndrome

Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine Response

Epidemiological studies have demonstrated that survivors of acute burn trauma are at long-term increased risk of developing a range of morbidities. The mechanisms underlying this increased risk remain unknown. This study aimed to determine whether burn injury leads to sustained immune dysfunction that may underpin long-term morbidity. Plasma and peripheral blood mononuclear cells were collected from 36 pediatric burn survivors >3 years after a non-severe burn injury (<10% total body surface area) and from age/sex-matched non-injured controls.

Meet the Finalists: Illuminate PitchFest 2024

Illuminate PitchFest is back! We are excited to introduce you to 10 trailblazing researchers who will be taking to the stage this February to pitch their bold and bright ideas.

Mums Minds Matter

Amy Jenny Susan Desiree Keerthi Finlay-Jones Downs Prescott Silva Kottampally BPsych(Hons), MPsych(Clinical), MHealthEcon, PhD (Clin Psych) BApplSci