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Prospective Student Evening

Students met ORIGINS team at the recent Prospective Student Evening at Telethon Kids Institute.

Our current collaborators

A list of organisations that currently collaborate with ORIGINS.

For researchers & collaborators

ORIGINS provides a cost-effective research enabling platform for those looking to conduct research in child and family health.

WA Cohorts Network welcomes FHRI Funding Announcement

The State Government has launched the new WA Cohort Studies Research Project Support Program, recognising the value and importance of the three major cohort studies in WA.

Sub-project initiation & approval process

Accessing the ORIGINS cohort, database or biological samples involves a process of review and approval.

ORIGINS Biobank

The ORIGINS Biobank is collecting biological samples from participant families at 10 timepoints between the time of pregnancy and the child turning five years of age.

ORIGINS Databank

ORIGINS is collecting physiological, biological and clinical data from the mother, partner/father and child at numerous points to track development and change.

The SunPreg Study

Determining the associations of sun exposure in early life on the development of non-communicable diseases.

Cord blood t cells expressing high and low pkcζ levels develop into cells with a propensity to display th1 and th9 cytokine profiles, respectively

ow Protein Kinase C zeta (PKCζ) levels in cord blood T cells (CBTC) have been shown to correlate with the development of allergic sensitization in childhood. However, little is known about the mechanisms responsible. We have examined the relationship between the expression of different levels of PKCζ in CBTC and their development into mature T cell cytokine producers that relate to allergy or anti‐allergy promoting cells.

Pediatric Burn Survivors Have Long-Term Immune Dysfunction With Diminished Vaccine Response

Epidemiological studies have demonstrated that survivors of acute burn trauma are at long-term increased risk of developing a range of morbidities. The mechanisms underlying this increased risk remain unknown. This study aimed to determine whether burn injury leads to sustained immune dysfunction that may underpin long-term morbidity. Plasma and peripheral blood mononuclear cells were collected from 36 pediatric burn survivors >3 years after a non-severe burn injury (<10% total body surface area) and from age/sex-matched non-injured controls.