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Showing results for "early life"

Maternal Pre-pregnancy Body Mass Index and Offspring Temperament and Behavior at 1 and 2 Years of Age

Recent research suggests that fetal exposure to increased maternal body mass index (BMI) during pregnancy may be associated with psychopathology later in life.

Epigenomic variability is associated with age-specific naïve CD4 T cell response to activation in infants and adolescents

Childhood is a critical period of immune development. During this time, naïve CD4 T cells undergo programmed cell differentiation, mediated by epigenetic changes, in response to external stimuli leading to a baseline homeostatic state that may determine lifelong disease risk. However, the ontogeny of epigenetic signatures associated with CD4 T cell activation during key developmental periods are yet to be described.

Validation of monoclonal anti-PKC isozyme antibodies for flow cytometry analyses in human T cell subsets and expression in cord blood T cells

We have undertaken to validating the specificity of commercially available antibodies marketed for flow cytometry to measure PKCα, βI, βII, δ, ε, η, θ, ζ, ι/λ and μ

Planetary Health: From the Wellspring of Holistic Medicine to Personal and Public Health Imperative

Here, we explore the history of planetary health and describe its relevance to contemporary healthcare

Narrative Medicine Meets Planetary Health: Mindsets Matter in the Anthropocene

We argue that the principles and practice of narrative medicine can be applied on a larger scale, one with planetary health in mind

Preventive medicine for person, place, and planet: Revisiting the concept of high-level wellness in the planetary health paradigm

Here, we discuss the relevance of planetary health in the era of personalized medicine, gross environmental concerns, and a crisis of non-communicable diseases

The importance of the exposome and allostatic load in the planetary health paradigm

The concept of planetary health emphasizes that human health is intricately connected to the health of natural systems within the Earth's biosphere

Dysbiotic drift and biopsychosocial medicine: how the microbiome links personal, public and planetary health

Here we focus on the rapidly progressing microbiome science as a way to illustrate the pathways by which exposure to biodiversity supports health

Histone modifications and their role in epigenetics of atopy and allergic diseases

This review covers basic aspects of histone modification and the role of posttranslational histone modifications in the development of allergic diseases