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Meta-analysis identifies seven susceptibility loci involved in the atopic marchEczema often precedes the development of asthma in a disease course called the 'atopic march'.
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Safety and Immunogenicity of Neonatal Pneumococcal Conjugate Vaccination in Papua New Guinean Children: A Randomised Controlled TrialWe conducted an open randomized controlled trial in Papua New Guinea to compare safety, immunogenicity and priming for memory of 7-valent PCV (PCV7) given in...
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Ontogeny of toll-like and NOD-like receptor-mediated innate immune responses in Papua New Guinean infantsStudies addressing the ontogeny of the innate immune system in early life have reported mainly on Toll-like receptor (TLR) responses in infants living in...
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Febrile respiratory illnesses in infancy and atopy are risk factors for persistent asthma and wheezeThe aim of this study was to explore associations between severe respiratory infections and atopy in early childhood with persisting wheeze and asthma.
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Global allergy forum and second davos declaration 2013 allergy: Barriers to cure - Challenges and actions to be takenThe epidemic increase in the prevalence of allergic disease, which first started in the industrialized countries in the 1960s, may have reached a peak in the...
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A genomics-based approach to assessment of vaccine safety and immunogenicity in childrenThis methodology has significant potential to identify covert interactions between inflammatory pathways triggered by vaccination, and as such may be a...
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Toll-like receptor 7 function is reduced in adolescents with asthmaAnti-viral innate immune responses may be impaired in asthma, although the mechanisms are not well understood.
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Th2-associated immunity to bacteria in asthma in teenagers and susceptibility to asthmaBacterial colonisation of the airways is associated with increased risk of childhood asthma
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Evaluation of impact of 23 valent pneumococcal polysaccharide vaccine following 7 valent pneumococcal conjugate vaccine in Australian Indigenous children.Background: High incidence and serotype diversity of invasive pneumococcal disease (IPD) in Indigenous children in remote Australia led to rapid introduction of
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Gene polymorphisms, breast-feeding, and development of food sensitization in early childhoodThe effect of breast-feeding on the development of allergic disease is uncertain