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Research

No role for neutrophil elastase in influenza-induced cellular recruitment, cytokine production or airway hyperresponsiveness in mice

Previous studies have suggested that in vitro modulation of neutrophil chemokines and inflammatory cytokines by neutrophil elastase (NE) does not translate to t

Research

Trajectories of childhood body mass index are associated with adolescent sagittal standing posture

The objective of this study is to identify distinct age-related trajectory classes of body mass index (BMI) z-scores from childhood to adolescence

Research

Neonatal immune function and inflammatory illnesses in later life: lessons to be learnt from the developing world?

With the emergence of allergic and autoimmune diseases in populations that have started to transit to a western lifestyle, there has been an increasing...

Research

Stability of interleukin 8 and neutrophil elastase in bronchoalveolar lavage fluid following long-term storage

Interleukin-8 (IL-8) and neutrophil elastase (NE) are commonly measured markers of inflammation in bronchoalveolar lavage (BAL) fluid from patients with cystic

Research

Structural and IgE binding analyses of recombinant Der p 2 expressed from the hosts Escherichia coli and Pichia pastoris

The house dust mite allergen Der p 2 is one of the most important indoor allergens associated with allergic disease.

Research

Unpacking the complex nature of the autism epidemic

This paper discusses changes in diagnostic criteria, decreasing age at diagnosis, improved case ascertainment, diagnostic substitution, and social influences.

Adolescent Health and Wellbeing

The Adolescent Health and Wellbeing team works in partnership with young people to understand their priority needs and the best ways to address these. This includes informing evidence-based policies and co-designing accessible and responsive health services.

Chronobiology

The Chronobiology team works to understand the factors that contribute to poor lung and heart function in newborn infants and find ways to prevent heart and lung disease.

Research

The impact of Influenza infection during early life on immune development

This study will investigate the why disease is worse in infants and how early life viral infection impacts the developing immune system.