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Showing results for "early life"
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Children’s regenerative and genetic medicine programThe project aims to build capacity in regenerative medicine for children with respiratory diseases.
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COVID-19 in children. II: Pathogenesis, disease spectrum and managementThe global disruption of the COVID-19 pandemic has impacted the life of every child either directly or indirectly. This review explores the pathophysiology, immune response, clinical presentation and treatment of COVID-19 in children, summarising the most up-to-date data including recent developments regarding variants of concern.
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Official ERS technical standard: Global Lung Function Initiative reference values for static lung volumes in individuals of European ancestryMeasurement of lung volumes across the life course is critical to the diagnosis and management of lung disease. The aim of the study was to use the Global Lung Function Initiative methodology to develop all-age multi-ethnic reference equations for lung volume indices determined using body plethysmography and gas dilution techniques.
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Recurrent MET fusion genes represent a drug target in pediatric glioblastomaWe identified previously unidentified gene fusions involving the MET oncogene in pediatric glioblastoma
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Caesarean section and risk of autism across gestational age: a multi-national cohort study of 5 million birthsThe positive association between caesarean section (CS) and autism spectrum disorder (ASD) may be attributed to preterm delivery.
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Characterizing the risk of respiratory syncytial virus in infants with older siblings: a population-based birth cohort studyOur results lend support to a vaccination strategy which includes family members in order to provide maximum protection for newborn babies.
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Outcomes and endpoints reported in studies of pulmonary exacerbations in people with cystic fibrosis: A systematic reviewThere is no consensus about which outcomes should be evaluated in studies of pulmonary exacerbations in people with cystic fibrosis (CF). Outcomes used for evaluation should be meaningful; that is, they should capture how people feel, function or survive and be acknowledged as important to people with CF, or should be reliable surrogates of those outcomes. We aimed to summarise the outcomes and corresponding endpoints which have been reported in studies of pulmonary exacerbations, and to identify those which are most likely to be meaningful.
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Standardizing clinical care measures of rheumatic heart disease in pregnancy: A qualitative synthesisPregnancy provides an opportunity to strengthen health system responses and address whole-of-life health for women with rheumatic heart disease
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Adolescent peer aggression and its association with mental health and substance use in an Australian cohortProspective longitudinal birth cohort data was used to examine the association between peer aggression at 14yrs and mental health and substance use at 17yrs...
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Glioma-specific Domain IV EGFR cysteine mutations promote ligand-induced covalent receptor dimerization and display enhanced sensitivityEpidermal growth factor receptor (EGFR) is over-expressed in many brain tumors. This paper examines mutations the EGFR that make the cell it is produced in...