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Research

Relationship between environmental exposures in children and adult lung disease: the case for outdoor exposures

There is a growing understanding that chronic respiratory diseases in adults have their origins in early life

Research

Do early-life viral infections cause asthma?

Epidemiologic associations between viral lower respiratory infections (LRIs) and asthma in later childhood are well known

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UV exposure and protection against allergic airways disease

Asthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity.

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Toward improved prediction of risk for atopy and asthma among preschoolers: A prospective cohort study

Atopy and asthma are commonly initiated during early life, and there is increasing interest in the development of preventive treatments for at-risk children.

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Providing feedback on adherence increases use of preventive medication by asthmatic children

This study investigates the impact of measuring adherence and providing feedback on medication usage by children with unstable asthma.

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The importance of environment on respiratory genotype/phenotype relationships in the Inuit

This study aimed to investigate the effects of different macro-environments on asthma genotype-phenotype associations in 2 geographically separated populations

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Toll-like receptor 7 function is reduced in adolescents with asthma

Anti-viral innate immune responses may be impaired in asthma, although the mechanisms are not well understood.

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Vector fields of risk: A new approach to the geographical representation of childhood asthma

One of the major challenges in health studies with a spatial dimension is to produce valid and meaningful geographical representations of risk.

Research

Expression of kinin receptors on eosinophils: comparison of asthmatic patients and healthy subjects

The aims of this study were to investigate kinin receptor expression on eosinophils of asthmatic and healthy subjects