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Research

Lentivirus-mediated gene transfer of interleukin 10 to the ovine and human cornea

Gene transfer to a donor cornea ex vivo can modulate corneal graft failure in experimental animal models. We compared a lentiviral vector (LV) carrying...

Research

Relationship between environmental exposures in children and adult lung disease: the case for outdoor exposures

There is a growing understanding that chronic respiratory diseases in adults have their origins in early life

Research

Vector fields of risk: A new approach to the geographical representation of childhood asthma

One of the major challenges in health studies with a spatial dimension is to produce valid and meaningful geographical representations of risk.

Research

Hepatic iron loading in mice increases cholesterol biosynthesis

Iron and cholesterol are both essential metabolites in mammalian systems, and too much or too little of either can have serious clinical consequences

Research

Rates and types of hospitalisations for children who have subsequent contact with the child protection system

To determine whether children who have child maltreatment allegation or substantiation have a higher rate of general hospital admissions and injury related admi

Research

Monocytes from children with clinically stable cystic fibrosis show enhanced expression of Toll-like receptor 4

Lung disease in patients with cystic fibrosis (CF) is characterized by recurrent bacterial respiratory infections and intense airway inflammation.

Research

The factor structure of the eating disorder examination in clinical and community samples

We investigated whether children who are heavier at birth have an increased risk of type 1 diabetes

Research

Gross Motor Profile in Rett Syndrome as Determined by Video Analysis

This study used video supplemented by parent report data to describe the gross motor profile in females with Rett syndrome (n=99) and to investigate...

Airway Epithelial Research

The Airway Epithelial Research Team is investigating the role of the epithelium in the development of airway diseases including asthma, cystic fibrosis and lung transplant rejection.

Research

Early progressive encephalopathy in boys and MECP2 mutations

MECP2 mutations mainly occur in females with Rett syndrome. Mutations have been described in 11 boys with progressive encephalopathy...