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Research
PKC activation promotes maturation of cord blood T cells towards a Th1 IFN-γ propensityA significant number of babies present transiently with low protein kinase C zeta (PKCζ) levels in cord blood T cells, associated with reduced ability to transition from a neonatal Th2 to a mature Th1 cytokine bias, leading to a higher risk of developing allergic sensitisation, compared to neonates whose T cells have 'normal' PKCζ levels. However, the importance of PKCζ signalling in regulating their differentiation from a Th2 to a Th1 cytokine phenotype propensity remains undefined.
Research
Beyond Plants: The Ultra-Processing of Global Diets Is Harming the Health of People, Places, and PlanetGlobal food systems are a central issue for personal and planetary health in the Anthropocene. One aspect of major concern is the dramatic global spread of ultra-processed convenience foods in the last 75 years, which is linked with the rising human burden of disease and growing sustainability and environmental health challenges.
Research
The feasibility of a digital health approach to facilitate remote dental screening among preschool children during COVID-19 and social restrictionsTele-dentistry can be useful to facilitate screening of children, especially those living in rural and remote communities, and during the COVID-19 pandemic. This study evaluated the feasibility of tele-dental screening for the identification of early childhood caries (ECC) in preschoolers using an app operated by their parents with remote review by oral-health therapists.
News & Events
New evidence shows timely introduction of peanuts and eggs reduces allergy risksFamilies who introduce peanut butter and eggs to their baby’s diet at around six months of age can significantly reduce the chances of them developing a life-threatening allergy, according to a new study published in the Journal of Allergy and Clinical Immunology – In Practice.
News & Events
Tackling allergy prevention in early lifeThe Childhood Allergy and Immunology Research Team at The Kids Research Institute Australia are currently conducting four studies, through ORIGINS, investigating nutritional strategies in the diets of mothers and babies and how these may reduce the development of allergies.
News & Events
Child health and obesity the focus of international built environment studyResearch data from more than one million Australian and Welsh children will be examined to help better understand how the built environment affects child health and obesity, as part of an international research project to be co-led by The Kids Research Institute Australia.
Research
Comparison of experiences in two birth cohorts comprising young families with children under four years during the initial Covid-19 lockdown in Australia and the UK: A qualitative studyThis study aims to understand the experience and impact of the initial COVID-19 lock-down in young families with children aged below 4 years. Free text questions were administered to participants in the ORIGINS (Australia) and Born in Bradford (UK) cohort studies to collect qualitative information on worries, concerns and enjoyable experiences during the pandemic.
News & Events
New FHRI funding to support research helping kids have a healthier start to lifeORIGINS has secured $500,000 in funding from the WA Government’s Future Health Research and Innovation (FHRI) Fund.
News & Events
Shopping For Data to Drive DiscoveriesWhat if researchers could shop for different data to help uncover how, when and why chronic conditions such as asthma, obesity, allergies and poor mental health develop?
News & Events
ORIGINS Ch7 News StoryORIGINS featured on Channel 7 News recently with two family stories of how ORIGINS changed their lives.