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Reduced transforming growth factor β1 (TGF-β1) in the repair of airway epithelial cells of children with asthma

Evidence into the role of TGF-β1 in airway epithelial repair in asthma is still controversial. This study tested the hypothesis that the reduced TGF-β1 levels previously observed in paediatric asthmatic airway epithelial cells directly contribute to the dysregulated repair seen in these cells.

Kirstin Pascoe

Honorary Team Member

A diagnostic test for acute rheumatic fever (pilot study)

Currently there are no diagnostic tests for ARF, and no treatments targeting immune responses to improve disease outcomes.

Custom mental health app empowers new mums with lifelong wellbeing skills

ORIGINS Co-Director, Dr Jackie Davis, collaborated with researchers at The Kids to develop and pilot the Mums Minds Matter study.

Rare case of spontaneous simultaneous extensive subcutaneous emphysema, bilateral pneumothoraces, pneumomediastinum and pneumorrhachis

Nick Gottardo MBChB FRACP PhD Co-Head, Brain Tumour Research team; Head of Oncology and Haematology, Perth Children’s Hospital nicholas.gottardo@

The case for DNA methylation based molecular profiling to improve diagnostic accuracy for central nervous system embryonal tumors (not otherwise specified) in adults

We report the case of a 45-year-old woman who was diagnosed with a NOS based on immunohistochemical analysis of the patient's tumor at diagnosis.

Diabetes in Schools milestone

The Diabetes in Schools team at the Perth Children’s Hospital have just reached a huge milestone – 1000 school visits!

‘We do what we can as soon as we can’ Alcohol and Other Drug workforce perspectives on preventing and responding to prenatal alcohol exposure

Evidence based strategies are needed to enhance the ability of the Alcohol and Other Drugs (AOD) sector to prevent prenatal alcohol exposure (PAE) and harms including Fetal Alcohol Spectrum Disorder (FASD). In Australia FASD prevention research has largely focused on primary care and child development sectors, while little research has been conducted with AOD services providing comprehensive support to high risk women.

Jenna Palumbo

Director of Innovation and Impact

Participate in CDKL5 Research

Participate in our CDKL5 research to help advance research outcomes in the CDKL5 research field by our children's health specialist researchers.