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Target validation of the inosine monophosphate dehydrogenase (IMPDH) gene in Cryptosporidium using Phylomer® peptidesCryptosporidiosis, a gastroenteric disease characterised mainly by diarrheal illnesses in humans and mammals is caused by infection with the protozoan...
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Will Global Climate Change Alter Fundamental Human Immune Reactivity: Implications for Child Health?We postulate several mechanisms whereby climate change sensitive exposures and conditions will subtly impair aspects of the human immune response
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Perception of pediatric pain: A comparison of postoperative pain assessments between child, parent, nurse, and independent observerDifferences in the assessment of pediatric pain between children, parents, nurses, and independent observers in the acute postoperative setting
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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010Reliable and timely information on the leading causes of death in populations, and how these are changing, is a crucial input into health policy debates.
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A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990-2010Quantification of the disease burden caused by different risks informs prevention by providing an account of health loss different to that provided by a...
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Ethnic and gender differences in rates of congenital adrenal hyperplasia in Western Australia over a 21 year periodThe aim was to evaluate the incidence, sex distribution, ethnicity, age at diagnosis, clinical presentation and morbidity of all childhood-onset congenital...
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The use of an automated, portable glucose control system for overnight glucose control in adolescents and young adults with type 1 diabetesA key milestone in progress towards providing an efficacious and safe closed-loop artificial pancreas system for outpatient use is the development of fully...
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Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitisAtopic dermatitis (AD) is a commonly occurring chronic skin disease with high heritability. Apart from filaggrin (FLG), the genes influencing atopic...
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Low intake of B-vitamins is associated with poor adolescent mental health and behaviourThe current prevalence of mental health problems in Western populations is approximately 20% and half of all adult mental health disorders are estimated to...
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A comparison of activity, participation and quality of life in children with and without spastic diplegia cerebral palsyNew PageThe aim of this study wa to measure activity, participation and QoL in children with CP and to determine how these differ from a comparable group of...