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Lung function trajectories throughout childhood in survivors of very preterm birth: a longitudinal cohort studyLung function trajectories are impaired in survivors of very preterm birth
Research
Calculation of the age of the first infection for skin sores and scabies in five remote communities in northern AustraliaPrevalence of skin sores and scabies in remote Australian Aboriginal communities remains unacceptably high, with Group A Streptococcus (GAS) the dominant pathogen. We aim to better understand the drivers of GAS transmission using mathematical models.
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The potential of antisense oligonucleotide therapies for inherited childhood lung diseasesAntisense oligonucleotides are an emerging therapeutic option to treat diseases with known genetic origin. In the age of personalised medicines, antisense oligonucleotides can sometimes be designed to target and bypass or overcome a patient's genetic mutation, in particular those lesions that compromise normal pre-mRNA processing. Antisense oligonucleotides can alter gene expression through a variety of mechanisms as determined by the chemistry and antisense oligomer design.
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T-cell responses against rhinovirus species A and C in asthmatic and healthy childrenInfections by RV species A and C are the most common causes of exacerbations of asthma and a major cause of exacerbations of other respiratory disease.
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Adolescents' Perspectives on a Mobile App for Relationships: Cross-Sectional SurveyAdolescents were likely to use a mobile phone app for relationship support, and use was not influenced by background characteristics
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Educational inequality across three generations in AustraliaUsing a dataset of Australian children, we have the opportunity to not only investigate the transfer of educational resources across 3 generations in Australia.
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Sugar-sweetened beverage intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta-analysisWe think that variants in genes involved in fructose metabolism and ChREBP-FGF21 pathway interacts with SSB intake to exacerbate associations with SSB intake.
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Identification of health risk behaviours among adolescent refugees resettling in Western AustraliaWe aim to identify health risk behaviours among adolescent refugees resettling in WA and assess the feasibility of using a standardised questionnaire.
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Assessing motor skills to inform a fetal alcohol spectrum disorder diagnosis focusing on persons older than 12 years: a systematic review of the literatureA systematic review of current evidence using various electronic databases was conducted. Studies were appraised using a recognised clinical appraisal tool.
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Lessons learned in the development of sustained release penicillin drug delivery systems for the prophylactic treatment of rheumatic heart disease (RHD)The current prophylactic treatment to prevent rheumatic heart disease requires four-weekly intramuscular injection of a suspension of the poorly soluble benzathine salt form of penicillin G (BPG) often for more than 10 years. In seeking to reduce the frequency of administration to improve adherence, biodegradable polymer matrices have been investigated.