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Research

Evolution of pulmonary inflammation and nutritional status in infants and young children with cystic fibrosis

Improved nutrition is the major proven benefit of newborn screening programmes for cystic fibrosis (CF) and is associated with better clinical outcomes.

Research

Responsiveness of the human airway in vitro during deep inspiration and tidal oscillation

In healthy individuals, deep inspiration produces bronchodilation and reduced airway responsiveness, which may be a response of the airway wall to mechanical...

Research

Extent of metabolic risk in adolescent girls with features of polycystic ovary syndrome

The objective of this study was to determine prevalence of metabolic syndrome in adolescents with polycystic ovary syndrome (PCOS)

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The placenta and neurologic and psychiatric outcomes in the child: Study design matters

Much information exists about functions of the human placenta and about potential mechanisms by which the placenta may influence human health or disease...

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Linking MECP2 and pain sensitivity: the example of Rett syndrome

This study investigated the nature and prevalence of atypical pain responses in Rett syndrome and their relationships with specific MECP2 mutations.

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Evidence for associations between the purinergic receptor P2X(7) (P2RX7) and toxoplasmosis

Congenital Toxoplasma gondii infection can result in intracranial calcification, hydrocephalus and retinochoroiditis. Acquired infection is commonly associated

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UV inhibits allergic airways disease in mice by reducing effector CD4 T cells

In human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4

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Decreased fibronectin production significantly contributes to dysregulated repair of asthmatic epithelium

In human asthma, and experimental allergic airways disease in mice, antigen-presenting cells and CD4(+) effector cells at the airway mucosa orchestrate, and CD4

Research

Health professionals addressing alcohol use with pregnant women in Western Australia

Health professionals have an important role to play in preventing prenatal alcohol exposure

Research

Contribution of an intrinsic lag of continuous glucose monitoring systems to differences in measured and actual glucose concentrations

Current continuous glucose monitoring (CGM) systems measure glucose levels in the interstitial fluid to estimate blood glucose concentration.