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National funding for bright ideas targeting ear infections and dangerous fungi

Two projects led by The Kids Research Institute Australia have been awarded more than $2.5 million to fund innovative ideas focused, respectively, on combating persistent ear infections and investigating how dangerous fungi invade the bodies of immunocompromised people.

Optimising a 6-plex tetanus-diphtheria-pertussis fluorescent bead-based immunoassay

Small volume assays are required for large-scale research studies and in particular paediatric trials, where multiple measures are required from a single sample. Fluorescent bead-based technology (Bioplex/Luminex) allows high through-put and simultaneous quantification of multiple analytes in a single test. This technology uses sets of microspheres, each with a unique spectral address that can be coated with a different antigen of interest.

Acellular Pertussis Vaccine Given in the Week After Birth Does Not Impair Antibody Responses to Later Childhood Doses

A birth acellular pertussis vaccine may be a valuable alternative for immunity against infant pertussis when a pregnancy pertussis vaccine has not been administered. We assessed whether a birth dose may impair immunoglobulin G (IgG) responses to childhood pertussis boosters.

Immunogenicity and Safety of a 2 + 1 DTPa Priming Schedule in Australian Infants and the Impact of Maternally Derived Antibodies on Pertussis Antibody Responses up to 4 Years of Age

We assessed the impact of maternally derived pertussis antibodies on infant responses to a 2 + 1 vaccine schedule (6 weeks, 12 weeks, and 12 months). Infants with baseline antibodies showed lower IgG responses following the primary vaccination series, but this did not impair booster responses at 4 years of age.

Stan Perron Charitable Foundation grants back ambitious research projects

Eleven researchers from The Kids Research Institute Australia will benefit from the latest round of Stan Perron Charitable Foundation Research Fellowship and Platform grants, with two researchers receiving prestigious Perron Platform grants and a further ten awarded Research Fellowships.

Top five things you should know about the measles

Dr Tom Snelling from The Kids explains the top five things you should know about the virus and why having the measles vaccine is so important.

Six-minute Strep A tests dramatically cut wait time in remote settings

Children at risk of potentially life-threatening Strep A infections no longer have to wait five days for timely treatment, thanks to a The Kids Research Institute Australia study conducted in the remote Kimberley region of Western Australia.

Sarah Brazier

Senior Program Manager, Wesfarmers Centre of Vaccines & Infectious Diseases

Local business to support Aboriginal ear health program

Every year 650,000 Australian children suffer from recurrent or chronic middle ear infections called otitis media (OM).

Ear Explorers shows latest video technology helps ear disease diagnosis

Findings from The Kids Research Institute Australia’s ‘Ear Explorers’ real-life research project undertaken as part of the 2019 Telethon weekend, found short videos were more helpful than photos when making a diagnosis.