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Research

Cochrane corner: hearing aids for mild to moderate hearing loss in adults

The evidence supports the widespread provision of hearing aids as the first-line clinical management for those seeking help for hearing difficulties

Research

Higher Serum Immunoglobulin G3 Levels May Predict the Development of Multiple Sclerosis in Individuals With Clinically Isolated Syndrome

IgG3 levels and proportions of IgG3 (%IgG) in serum at CIS diagnosis were inversely correlated with the time until conversion to MS

Research

Exposure to chorioamnionitis alters the monocyte transcriptional response to the neonatal pathogen Staphylococcus epidermidis

Our findings suggest that prenatal exposure to inflammation may alter the risk of sepsis in preterm infants partly by modulation of monocyte responses to pathogens

Research

Tryptophan and arginine catabolic enzymes and regulatory cytokines in clinically isolated syndrome and multiple sclerosis

Higher IDO and ARG expression in clinically isolated syndrome and multiple sclerosis provides one sustained homeostatic mechanism to control multiple sclerosis-associated inflammation

Research

Structure-function relationships of the neisserial EptA enzyme responsible for phosphoethanolamine decoration of lipid A: Rationale for drug targeting

This review concentrates on the phosphoethanolamine decoration of lipid A in the pathogenic species of the genus Neisseria

Research

Airway function in infancy is linked to airflow measurements and respiratory symptoms from childhood into adulthood

Lung airflow measurements track from birth into early adulthood, suggesting a permanent and stable airway framework is laid down in the antenatal period

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Dysregulated IL-1β-GM-CSF Axis in Acute Rheumatic Fever That Is Limited by Hydroxychloroquine

We propose that hydroxychloroquine could be repurposed to reduce the risk of rheumatic heart disease after acute rheumatic fever

Research

Maternal pre-pregnancy weight and autistic-like traits among offspring in the general population

This study provides further evidence that maternal pre-pregnancy obesity is associated with autism-like behaviors in offspring

Research

Investigating falls in adults with intellectual disability living in community settings and their experiences of post-fall care services

This study will determine the rate of falls among older adults with ID living in community based settings, which will assist to identify the extent of this problem

Research

No relationship between autistic traits and salivary testosterone concentrations in men from the general population

The current data add to the increasing evidence for the lack of relationship between autistic traits and postnatal levels of testosterone in men