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COVID-19 Research Update
ORIGINS is no longer offering courier services or home collection of samples.
The PLAYCE Cohort was established to investigate how movement behaviours change over early to late childhood, across key behaviour settings and relationships with health and development
Aspergillus is increasingly associated with lung inflammation and mucus plugging in early cystic fibrosis disease during which conidia burden is low and strains appear to be highly diverse. It is unknown whether clinical Aspergillus strains vary in their capacity to induce epithelial inflammation and mucus production.
Chronic airway injury and dysregulated repair programs are evident in airway epithelium obtained from patients with bronchiolitis obliterans syndrome
Apically located tight junctions in airway epithelium perform a fundamental role in controlling macromolecule migration through paracellular spaces.