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CP Movetime: A wearable sensor and user interface to reduce sedentary behaviours in non-ambulant children and youth with cerebral palsy

CP Movetime aims to establish and test a technology-based application to improve health outcomes by monitoring device measured sedentary behaviours in non-ambulant children and youth with cerebral palsy.

DEFEND CF: Biomarkers to define the treatment end-point for pulmonary exacerbations in cystic fibrosis

Sensitive and reliable tests are required to monitor lung disease severity in cystic fibrosis.

Determinants of incomplete vaccination and non-vaccination among WA children

Tom Snelling BMBS DTMH GDipClinEpid PhD FRACP Head, Infectious Disease Implementation Research 08 6319 1817 tom.snelling@thekids.org.au Head,

Relationships between depression and anxiety symptoms scores and blood pressure in young adults

This study aimed to assess the relationships among BP, depression and anxiety symptom scores and self-reported history of depression in young adults.

Determinants of prenatal alcohol exposure among Aboriginal women in the Pilbara: Developing a statistically validated model of prenatal alcohol consumption for evidence based intervention development

Investigators: Dave Tucker (PhD candidate), Associate Professor Roz Walker, Dr Martyn Symonds, Dr Nyanda McBride The overarching aim of the proposed

Global, regional, and national incidence, prevalence, and years lived with disability for 328 diseases and injuries for 195 countries, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

Jonathan Carapetis AM AM MBBS FRACP FAFPHM PhD FAHMS Executive Director; Co-Head, Strep A Translation; Co-Founder of REACH 08 6319 1000 contact@

Developing a ‘Food Atlas’ for Western Australia to map, measure and monitor food access

This unique interdisciplinary project, funded by Healthway, aims to develop a Food Atlas tool for mapping, measuring, and monitoring food access across Western Australia.

Systematic analysis of transcription start sites in avian development

CAGE in combination with single-molecule sequencing technology allows mapping of TSSs and genome-wide capture of promoter activities state cell populations.

Developing a human challenge model of GAS infection

NHMRC funding has been awarded for 4 years to Murdoch Childrens Research Institute for this project, with collaboration from Professor Jonathan Carapetis at The Kids.

Developing a novel therapeutic pipeline for antibiotic resistant bacterial lung infection in children: investigating and assessing the potential phage therapy

Antimicrobial resistance is a global health crisis, which has accelerated due to the overuse of antibiotics.

Probabilistic linkage of national immunisation and state-based health records for a cohort of 1.9 million births to evaluate Australia’s childhood immunisation program

To describe the process for assembling a linked study that will enable the conduct of population-based studies related to immunisation and immunisation policy.

Developing and characterising juvenile models of aggressive paediatric brain cancers for the evaluation of novel immunotherapies.

While profound treatment responses have been realised using immunotherapy for some cancer types, this is yet to be seen for paediatric brain cancer patients.

Comprehending the Health Informatics Spectrum: Grappling with System Entropy and Advancing Quality Clinical Research

We outline three scenarios from across the health spectrum where issues with health informatics are exemplified.

Developing new immune based therapies for neuroblastoma

Neuroblastoma is a complex childhood cancer of the nerve cells and the most common solid tumour in children outside of the brain. The average age of diagnosis is 1-2 years and tragically 50% of children with high-risk neuroblastoma lose their battle within five years.

Contemporary survival endpoints: An international diffuse intrinsic pontine glioma registry study

This study defines PFS and OS, and is the first describe post-progression survival in a large cohort of children with DIPG.

Development of a screening tool to identify safer biodiesels

Alexander Anthony Larcombe Kicic BScEnv (Hons) PhD BSc (Hons) PhD Honorary Research Fellow Head, Airway Epithelial Research; WA Cystic Fibrosis

Gestational age and school achievement: A population study

We examined gestational age from preterm to post-term against a national minimum standard for academic achievement in population data.

Epidemiology of seasonal influenza infection in pregnant women and its impact on birth outcomes

Results from this linked population study suggests that there are differences in maternal infection by virus type and support the provision of seasonal vaccines

Duration of general anaesthetic exposure in early childhood and long-term language and cognitive ability

Anaesthetic dose causing toxicity in animals has been evaluated, but the relationship between duration of VA exposure and development in children remains vague.

The global lung function initiative (GLI) network: Bringing the world’s respiratory reference values together

The Global Lung Function Initiative (GLI) Network has become the largest resource for reference values for routine lung function testing ever assembled.