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Trajectories of childhood immune development and respiratory health relevant to asthma and allergyOur findings demonstrate the utility of unsupervised analysis in elucidating heterogeneity in asthma pathogenesis
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Measuring the capacity of active video games for social interaction: The Social Interaction Potential Assessment toolThe Social Interaction Potential Assessment tool can assess Active Video Games potential to facilitate social interaction among players
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Respiratory Syncytial Virus Hospitalization During Pregnancy in 4 High-income Countries, 2010-2016This study addressed respiratory syncytial virus (RSV) infection during pregnancy
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Time to tackle rheumatic heart disease: Data needed to drive global policy dialoguesThis report provides an update on the contemporary global and regional policy landscapes relevant to rheumatic heart disease
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Potential for molecular testing for group a streptococcus to improve diagnosis and management in a high-risk population: A prospective studyImplementation of molecular testing could improve antibiotic use in this high-burden setting
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HLA-DR Class II expression on myeloid and lymphoid cells in relation to HLA-DRB1 as a genetic risk factor for visceral leishmaniasisTo understand how HLA-DR contributes to disease pathogenesis, we examined expression at the protein level in circulating myeloid and lymphoid cells of VL patients
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Determinants for progression from asymptomatic infection to symptomatic visceral leishmaniasis: A cohort studyWe confirmed the strong association between high DAT and/or rK39 titers and progression to disease among asymptomatic subjects
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A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastomaWe present a curated panel of 12 readily-usable, cell lines representing the spectrum of molecular subtypes of IDH-wildtype glioblastoma
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Cost-effectiveness analysis of routine screening using massively parallel sequencing for maturity-onset diabetes of the young in a pediatric diabetes cohortRoutine MPS screening for Maturity-onset diabetes of the young in the pediatric population with diabetes could reduce health system costs and improve patient QoL
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Use of a primary epithelial cell screening tool to investigate phage therapy in cystic fibrosisThis study demonstrates the feasibility of utilizing pre-clinical in vitro culture models to screen therapeutic candidates