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Medical Exemptions to Mandatory Vaccinations: The State of Play in Australia and a Pressure Point to WatchAustralia’s mandatory vaccination policies have historically allowed for non-medical exemptions, but this changed in 2016 when the Federal Government discontinued non-medical exemptions for childhood vaccination requirements. Australian states introduced further mandatory vaccination policies during the COVID-19 pandemic for a range of occupations including healthcare workers.
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PI3K/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine gliomaDiffuse midline glioma (DMG), including tumors diagnosed in the brainstem (diffuse intrinsic pontine glioma; DIPG), are uniformly fatal brain tumors that lack effective treatment.
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Financial toxicity of informal caregivers of colorectal cancer patients: A cross-sectional studyTo assess the level of financial toxicity of informal caregivers of colorectal cancer patients and explore the related key influencing factors.
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Editorial: Vaccines and immunization services during the pandemic era and beyondCitation: Amponsah-Dacosta E, Fulurija A, Afum-Adjei Awuah A, Mathema S, Wariri O. Editorial: Vaccines and immunization services during the pandemic
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Infant Whole-Cell Versus Acellular Pertussis Vaccination in 1997 to 1999 and Risk of Childhood Hospitalization for Food-Induced Anaphylaxis: Linked Administrative Databases Cohort StudyEvidence suggests that children who had received an initial priming dose of whole-cell pertussis (wP) vaccine, rather than acellular pertussis (aP) vaccine, had a lower risk of developing IgE-mediated food allergy, the most common cause of anaphylaxis-related hospital presentations of childhood.
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Associations between sun exposure, skin pH, and epidermal permeability in pregnancy: A longitudinal observational studyLittle is known about how sun exposure may affect the maternal skin barrier during pregnancy when many hormonal and physiological changes occur. In this longitudinal observational study, 50 pregnant women were recruited at 18-24 weeks' gestation, 25 in summer-autumn, and 25 in winter-spring. At three time points in pregnancy at 18-24, 28-30, and 36-38 weeks' gestation, participants completed a validated sun exposure questionnaire and had skin permeability and surface pH measured on the volar forearm.
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Incidence and survival for childhood cancer by endorsed non-stage prognostic indicators in AustraliaNick Gottardo MBChB FRACP PhD Head of Paediatric and Adolescent Oncology and Haematology, Perth Children’s Hospital; Co-head, Brain Tumour Research
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Nutritional Criminology: Why the Emerging Research on Ultra-Processed Food Matters to Health and JusticeThere is mounting concern over the potential harms associated with ultra-processed foods, including poor mental health and antisocial behavior. Cutting-edge research provides an enhanced understanding of biophysiological mechanisms, including microbiome pathways, and invites a historical reexamination of earlier work that investigated the relationship between nutrition and criminal behavior. Here, in this perspective article, we explore how this emergent research casts new light and greater significance on previous key observations.
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Risk factors for diagnosis and treatment delay among patients with multidrug-resistant tuberculosis in Hunan Province, ChinaMultidrug-resistant tuberculosis (MDR-TB) is a global health threat associated with high morbidity and mortality rates. Diagnosis and treatment delays are associated with poor treatment outcomes in patients with MDR-TB. However, the risk factors associated with these delays are not robustly investigated, particularly in high TB burden countries such as China.
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Combining Clinical With Cognitive or Magnetic Resonance Imaging Data for Predicting Transition to Psychosis in Ultra High-Risk Patients: Data From the PACE 400 CohortMultimodal modeling that combines biological and clinical data shows promise in predicting transition to psychosis in individuals who are at ultra-high risk. Individuals who transition to psychosis are known to have deficits at baseline in cognitive function and reductions in gray matter volume in multiple brain regions identified by magnetic resonance imaging.

News & Events
Good news for studentsThe Children’s Diabetes Centre welcomes a new Federal Government initiative to support children with Type 1 Diabetes in schools. The two-year $6 million schools education and training program will be implemented at every school with a student with Type 1 Diabetes.

News & Events
Georgia wants to be part of the solutionGeorgia Egan, 16,recently completed a six-month Hybrid Closed-Loop Outpatient Trial, the longest and largest at-home trial of a hybrid closed-loop insulin pump.

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ATAR special provisions still open for newly diagnosedThe deadline for ATAR exam special provisions is still open for newly diagnosed Type 1 Diabetes patients.

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Type 1 breakthroughChildren's Diabetes Centre co-director Professor Tim Jones talked to Medical Forum WA about the findings of the global landmark AdDIT trial.

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Montanna's diabetes dashA diabetes diagnosis is a shock at any time but spare a thought for the Rustens who jumped on a plane to Perth from Kununurra within an hour of diagnosis.

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Cholesterol and blood pressure drugs help teens with diabetesResearchers from the Children’s Diabetes Centre have had a lead role in a global adolescent Type 1 Diabetes study.

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T1D: Challenge acceptedOne step at a time … that’s the message Canadian Sebastien Sasseville wants kids living with Type 1 Diabetes to know when he talks about his T1D journey.

News & Events
Student the first to take part in world-first diabetes trialRead about Jake's journey as the first participant recruited to the Hybrid Closed Loop Trial, led by Children's Diabetes Centre, in the Midland Reporter.