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Maternal dietary intake in pregnancy and lactation and allergic disease outcomes in offspringAs the prevalence of allergic disease dramatically rises worldwide, prevention strategies are increasingly being considered.
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Effects of maternal dietary egg intake during early lactation on human milk ovalbumin concentration: A randomized controlled trialIncreased maternal egg ingestion is associated with increased breastmilk ovalbumin, and markers of immune tolerance in infants
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Early life nutrition and the opportunity to influence long-term health: an Australasian perspectiveThere is significant data to support the hypothesis that early life nutrition in the fetus, infant and young child can have profound effects on long-term health
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25-hydroxyvitamin D status of pregnant women is associated with the use of antenatal vitamin supplements and ambient ultraviolet radiationVitamin D deficiency in a predominantly white Caucasian cohort of pregnant women is less prevalent than has been reported in other studies
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In-utero exposures and the evolving epidemiology of paediatric allergyThis paper discusses the rising prevalence of allergic disease in children. This review article considers recent findings in the field of paediatric immune...
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In utero and postnatal vitamin D exposure and allergy riskThis review article examines the evidence of the impact of in utero and postnatal vitamin D exposure on allergy risk in childhood
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Nutritional Influences on Epigenetic Programming. Asthma, Allergy, and ObesityReliance on increasing use of dietary supplementation and fortification (eg, with folate) to compensate for increased consumption of processed foods is also...
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The PrEggNut Study – Maternal diet rich in eggs and peanuts to reduce food allergies: a randomised controlled trialDebbie Susan Palmer Prescott BSc BND PhD MBBS BMedSci PhD FRACP Head, Nutrition in Early Life Honorary Research Fellow debbie.palmer@uwa.edu.au
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Study Protocol for a Randomised Controlled Trial Investigating the Effects of Maternal Prebiotic Fibre Dietary Supplementation from Mid-Pregnancy to Six Months’ Post-Partum on Child Allergic Disease OutcomesInfant allergy is the most common early manifestation of an increasing propensity for inflammation and immune dysregulation in modern environments. Refined low-fibre diets are a major risk for inflammatory diseases through adverse effects on the composition and function of gut microbiota. This has focused attention on the potential of prebiotic dietary fibres to favourably change gut microbiota, for local and systemic anti-inflammatory effects.
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Impaired calcium influx underlies skewed T helper cell differentiation in children with IgE-mediated food allergiesReasons for Th2 skewing in IgE-mediated food allergies remains unclear. Clinical observations suggest impaired T cell activation may drive Th2 responses evidenced by increased atopic manifestations in liver transplant patients on tacrolimus (a calcineurin inhibitor). We aimed to assess differentiation potential, T cell activation and calcium influx of naïve CD4+ T cells in children with IgE-mediated food allergies.